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Uncovering Pompe Disease: Is it Muscle Weakness or Something More?
Podcast
The progression of Pompe disease happens quickly and can be fatal if untreated. Early diagnosis allows for prompt initiation of life-saving enzyme replacement therapy and prevents the development of irreversible muscle damage. Join Barbara Burton, MD, and John Bach, MD, as they discuss the clinical presentation, screening practices, and diagnosis of Pompe disease as well as strategies to maintain patient quality of life.
Identifying Patients With LS-SCLC Who Are Candidates for Consolidation Therapy
Case Study
Limited-stage small cell lung cancer (LS-SCLC) is an aggressive cancer with high relapse rates and poor overall survival rates with chemoradiotherapy. Join Chul Kim, MD, as he discusses strategies to integrate emerging clinical data and incorporate best practices for managing immune-related adverse effects associated with immune checkpoint inhibitors into treatment plans for patients with LS-SCLC.
Treating AML With CAR T: Recent Clinical Trial Data
Chapter
The immunological complexity of acute myeloid leukemia (AML) makes it difficult to utilize chimeric antigen receptor T-cell (CAR T) therapy. Despite this, promising strategies are being developed to overcome these challenges. Join Dr. Eunice Wang as she reviews clinical trial outcomes of CAR T therapy for AML, as recently presented at the 2024 American Society of Hematology annual conference.
Overview of R/R Multiple Myeloma Therapies With a Focus on CAR T-Cell Therapies
Chapter
Almost all patients with multiple myeloma (MM) relapse and then keep relapsing with remission duration decreasing with each subsequent line of treatment. For every new line of treatment, duration of therapy and treatment-free interval decrease, along with depth of response, while toxicities increase. Thankfully, there are more treatment options available now for patients with relapsed/refractory MM (RRMM) than ever before, which can hopefully improve prognosis for these patients. In this activity, we will go over the principles of RRMM therapeutic decision making, with a focus on chimeric antigen receptor (CAR) T-cell therapy, and when and how to incorporate this treatment modality into a patient’s therapeutic plan.
CAR T Options for DLBCL and FL
Webcast
Chimeric antigen receptor (CAR) T-cell therapies have been shown to produce deep and durable treatment responses in patients with chemotherapy-refractory non-Hodgkin lymphoma (NHL), a previously unmet need. Join Dr. Jason Westin and Dr. Caron Jacobson as they discuss clinical trial and real-world data supporting the use of CAR T-cells in both diffuse large B-cell lymphoma and follicular lymphoma.
Recurrence of Metastatic Esophageal Squamous Cell Carcinoma
Patient Simulator
For patients with advanced esophageal squamous cell carcinoma (ESCC), immune checkpoint inhibitors are providing an alternative to first- and second-line chemotherapy. This i-Human simulation with Dr. Sunnie Kim will walk through a patient-centered approach to biomarker testing, treatment, and management of immune-related adverse effects in a patient with recurrent metastatic ESCC.
Making Headway in MDS–Leveraging New IDH1/2-Targeted Strategies
Experts at Your Fingertips
Alzheimer's Disease Early Detection, Treatment, and Management of ARIA
Experts at Your Fingertips
Case Studies
Switching Treatment in Rheumatoid Arthritis After Inadequate Response to Multiple Anti-TNF Therapies
Case Study
In recent decades, disease-modifying antirheumatic drugs have changed the treatment landscape for rheumatoid arthritis (RA) therapy. However, it is not always clear when and how to change therapy in patients with RA with an inadequate response. Join Maria Greenwald, MD, FACR, in following the case of a 38-year-old woman who experiences inadequate response to tumor necrosis factor inhibitor therapy. When to switch therapies and her treatment options are discussed.
Managing a Patient Newly Diagnosed With LS-SCLC
Case Study
Limited-stage small cell lung cancer (LS-SCLC) is a highly aggressive disease with poor long-term survival rates, despite advances in chemoradiotherapy. Join Melinda L. Hsu, MD, as she discusses essential strategies to incorporate immune checkpoint inhibitors into treatment, manage immune-related adverse effects, and optimize care for patients with LS-SCLC.
Screening Strategies to Ensure Early Diagnosis and Treatment of AATD
Case Study
Alpha-1 antitrypsin deficiency (AATD) is underrecognized and undertreated. Join Dr. Cheryl Pirozzi in exploring the diagnosis and management of a 35-year-old man with AATD. Screening strategies and the current treatment paradigm for asymptomatic and symptomatic patients will be discussed.
Selecting Induction and Maintenance Therapy for a Patient With CIDP
Case Study
Timely diagnosis and early treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) can reduce the risk of permanent disability. Join Dr. Karissa Gable in exploring the diagnosis and management of a 52-year-old man with CIDP. The current treatment paradigm, including the use of novel therapies, will be discussed.
Positioning of New S1P Receptor Modulators to Optimize Patient Outcomes in UC
Case Study
Sphingosine-1-phosphate receptor modulators are a new oral treatment option for ulcerative colitis (UC). Join Michele Rubin, MSN, APRN, CNS-BC, CGRN, in reviewing how to integrate these new oral strategies into management for a 24-year-old woman with moderate to severe UC who experiences loss of efficacy on biologic therapy.
Managing a Patient With Acute Graft-Versus-Host Disease
Case Study
For patients who undergo allogeneic hematopoietic stem cell transplantation (HSCT), it is important to know how to recognize and manage acute graft-versus-host disease (aGVHD), a common complication that is associated with significant morbidity and mortality. Join Dr. Catherine J. Lee to practice clinical management of a 63-year-old patient with post-polycythemia vera myelofibrosis who developed aGVHD following HSCT. Current and emerging treatment strategies are explored.
Experts at Your Fingertips
Customize Your Own Panel Discussion
Build your own dynamic, interactive panel discussion in real-time from nationally recognized speakers' video streams. Designed to accommodate microlearning, Experts at Your Fingertips offers an interactive and customizable learning experience crafted from clinician perspectives along the health care journey that matters to you.
Making Headway in MDS–Leveraging New IDH1/2-Targeted Strategies
Panel Discussion
Alzheimer's Disease Early Detection, Treatment, and Management of ARIA
Panel Discussion
New Paradigms in the Treatment of Eosinophilic Esophagitis
Panel Discussion
Assimilating New Treatment Paradigms Into Melanoma Care
Panel Discussion
The Future Draws Near – Preparing for New MASH Therapies and Clinical Strategies
Panel Discussion
Advancing Care With Antibody-Drug Conjugates in Urothelial Carcinoma
Panel Discussion
Explore Activities
Featured
Strategies for Success: A Multidisciplinary Approach to Diagnosing and Managing Bladder Cancer
Real-World Strategies for Addressing Melanoma Management in Patients With Skin of Color
Shared Decision Making in the Treatment of a Patient with Obesity and T2DM
Metastatic Renal Cell Carcinoma: Integrating Patient Perspectives Into Management
Integrating Patient Values and Goals Into A Holistic Approach to Managing Obesity
iHuman Patient Simulator
Interactive Patient Simulator
Engage in an interactive real-world case simulation by interacting with patient and clinician avatars. Fallon will guide your exploration into a patient's health history as part of an accurate diagnosis of their illness and allows for mentorship through treatment decisions to achieve the highest level of patient outcomes.
Recurrence of Metastatic Esophageal Squamous Cell Carcinoma
iHuman Patient Simulator
Considerations for Initiating CAR T in Relapsed or Refractory Follicular Lymphoma
iHuman Patient Simulator
Sequencing Bispecific Antibodies With CAR-T in High-Risk/Aggressive RRMM
iHuman Patient Simulator
Managing a Patient With Newly-Diagnosed Unresectable Esophageal Squamous Cell Carcinoma
iHuman Patient Simulator
How to Sequence Therapies in a Patient With Relapsed CLL
iHuman Patient Simulator
Incorporating Noncovalent BTKi Therapies Into the Management of R/R CLL
iHuman Patient Simulator
Choice of Initial Treatment and Subsequent Therapies in Pediatric Eosinophilic Esophagitis
iHuman Patient Simulator
Chatbots
Converse with our trained chatbot in multiple therapeutic areas
Features clinician thought leader-provided and peer-reviewed content and informed through user generated feedback.
Podcasts
The State of HBV Care and Treatment
Podcast
Hepatitis B presents a huge health burden, affecting an estimated 2 million people in the US alone. In this podcast, our faculty, Dr. Paul Kwo and Dr. Mindie Nguyen, discuss the disease burden, as well as guideline-directed best practices for the screening, evaluation, and management of the disease and also talk about therapy targets and functional cure.
EoE: Picking the Right Tool For the Job
Podcast
Without a standardized approach to severity assessment, eosinophilic esophagitis (EoE) is challenging to evaluate and monitor. To address this, the Index of Severity in EoE (I-SEE) was developed by leading experts in collaboration with the American Gastroenterological Association (AGA) and is designed to be easily used in routine practice. In this episode, Drs Evan Dellon and Nirmala Gonsalves discuss challenges in assessing EoE severity and how I-SEE can help.
Treating Pompe Disease: Beyond the Guidelines
Podcast
Enzyme replacement therapy (ERT) has prolonged survival in infants and slowed progression of Pompe disease in children and adults. However, patients with Pompe disease continue to progress on ERT, and monitoring for disease progression and initiating newer therapies are crucial for maintaining motor and respiratory functions. Join Jennifer L. Cohen, MD and Urvi Desai, MD, as they discuss strategies on how to optimize therapy and review clinical trial data on available treatment options.
Improving Survival With HMA Maintenance Therapy in AML
Podcast
Which patients are the best candidates for maintenance therapy in acute myeloid leukemia (AML)? In this episode our faculty discuss the latest clinical evidence for using hypomethylating agents as maintenance therapy in AML and the patients that might gain the most benefit from them.
The Importance of the Genetic Landscape in Advancing AML Care
Podcast
In this episode our faculty discuss how the recognition of genetic mutations are influencing new targets and treatments for acute myeloid leukemia. What should clinicians know?
The Clock Is Ticking on ATTR-CM
Podcast
In this episode our faculty discuss the clinical manifestations and how to correctly diagnose transthyretin amyloid cardiomyopathy (ATTR-CM). What should clinicians know in order to make an accurate and timely diagnosis?
Finding a Needle in the Haystack: Diagnosing AL Amyloidosis
Podcast
Many of the initial symptoms of immunoglobulin light chain (AL) amyloidosis are nonspecific, delaying diagnosis and resulting in progressive organ dysfunction and ultimately irreversible organ failure. Early recognition is critical as prompt treatment initiation can limit accumulation of amyloid fibrils in end organs and prolong life. Join Shahzad Raza, MD, and Faiz Anwer, MD, as they discuss strategies for the early recognition and diagnosis of AL amyloidosis.
A Deeper Look at CIDP Diagnosis and Treatment
Podcast
The diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in patients who present with weakness and sensory disturbances is often complex and involves distinguishing it from other conditions that mimic CIDP. As the understanding of CIDP has evolved, guidelines on diagnosis and treatment of CIDP have been revised. Join Jeffrey Allen, MD, and Diana Castro, MD, as they discuss the application of updated diagnostic criteria to identify patients with typical CIDP and its variants, as well as review current recommended induction and maintenance therapies.
Webcasts
CAR T Options for DLBCL and FL
Webcast
Chimeric antigen receptor (CAR) T-cell therapies have been shown to produce deep and durable treatment responses in patients with chemotherapy-refractory non-Hodgkin lymphoma (NHL), a previously unmet need. Join Dr. Jason Westin and Dr. Caron Jacobson as they discuss clinical trial and real-world data supporting the use of CAR T-cells in both diffuse large B-cell lymphoma and follicular lymphoma.
I-SEE EoE: Using the App
Webcast
Eosinophilic esophagitis (EoE) has historically been challenging to evaluate due to the lack of a standardized approach to severity assessment. To address this, the Index of Severity for EoE (I-SEE) was developed by leading experts in collaboration with the American Gastroenterological Association (AGA) and is designed to be easily used in routine practice. In this activity, Drs. Evan Dellon, Emily McGowan, and Nirmala Gonsalves demonstrate how to use the I-SEE tool in clinical practice.
Acing the NTM-LD Diagnosis
Webcast
Nontuberculous mycobacterial (NTM) is an environmental bacteria that can cause pulmonary disease requiring complex treatment, often with suboptimal results. In this program, Drs. Griffith and McShane will discuss how to diagnose NTM lung disease, including common pitfalls in diagnosis, using case presentations to illustrate typical presentations of this disease.
Selecting and Sequencing Bispecific Antibody Therapy in Multiple Myeloma
Webcast
Join us for an engaging webcast that explores the latest research from the rapidly evolving relapsed/refractory multiple myeloma landscape, including clinical trial data supporting currently approved bispecific antibody therapy and emerging data to anticipate. Gain expert insights from Dr. Adam Cohen and Dr. Krina Patel that will equip you to optimize patient selection and treatment sequencing in this patient population.
Diagnosing Atopic Dermatitis in a Patient with Melanin-Rich Skin
Webcast
To accurately diagnose atopic dermatitis (AD) and assess disease severity, it is important for clinicians to be familiar with a range of AD presentations across skin tones. Join Dr. Ellen N. Pritchett in reviewing the diagnosis and severity assessment of a 23-year-old patient with active lesions on the trunk and extremities and a longstanding history of diffuse rash.
Strategies for Early Detection of MASH
Webcast
The past few years have seen many developments in noninvasive testing modalities for fibrosis in patients with liver steatosis. In this program, Dr. Noureddin will discuss the development of new serum and imaging tests that can help in the diagnosis of patients with metabolic steatohepatitis (MASH) and determine eligibility for treatment.
Improving Outcomes for Patients with ESCC
Webcast
Join medical oncologist, Manish Shah, MD and nurse practitioner Hilary Heyison, as they discuss clinical approaches to harmonize multidisciplinary care for the management of esophageal squamous cell cancer (ESCC). From frontline immunotherapeutic treatment options to shared decision-making strategies, this program will equip you with new insights to support you in caring for your patients with ESCC.
iHuman Patient Simulator
Interactive Patient Simulator
Engage in an interactive real-world case simulation by interacting with patient and clinician avatars. Fallon will guide your exploration into a patient's health history as part of an accurate diagnosis of their illness and allows for mentorship through treatment decisions to achieve the highest level of patient outcomes.
Recurrence of Metastatic Esophageal Squamous Cell Carcinoma
iHuman Patient Simulator
Considerations for Initiating CAR T in Relapsed or Refractory Follicular Lymphoma
iHuman Patient Simulator
Sequencing Bispecific Antibodies With CAR-T in High-Risk/Aggressive RRMM
iHuman Patient Simulator
Managing a Patient With Newly-Diagnosed Unresectable Esophageal Squamous Cell Carcinoma
iHuman Patient Simulator
How to Sequence Therapies in a Patient With Relapsed CLL
iHuman Patient Simulator
Incorporating Noncovalent BTKi Therapies Into the Management of R/R CLL
iHuman Patient Simulator
Choice of Initial Treatment and Subsequent Therapies in Pediatric Eosinophilic Esophagitis
iHuman Patient Simulator
Chatbots
Converse with our trained chatbot in multiple therapeutic areas
Features clinician thought leader-provided and peer-reviewed content and informed through user generated feedback.